LANOSTEROL REGULATES ABNORMAL AMYLOID ACCUMULATION IN LECS THROUGH THE MEDIATION OF CHOLESTEROL PATHWAY METABOLISM

Lanosterol regulates abnormal amyloid accumulation in LECs through the mediation of cholesterol pathway metabolism

Age-related cataract (ARC) is the predominant cause of global blindness, linked to the progressive aging of the lens, oxidative stress, perturbed calcium homeostasis, hydration irregularities, and modifications in crystallin proteins.Currently, surgical intervention remains the sole efficacious remedy, albeit carrying inherent risks of complication

read more

Biochemical Study of Mumijo in Uvs province, Mongolia

The authors cleared mumijo pentair hose by extractive and distil methods, defined pure output of natural mumijo and compared difference between these two methods.We defined the amount of dry and extractive substances, raw oil, antioxidant-rutin, vitamin C, fulvic acid, common nitrogen and total protein, content of protein amino acids, and mineral e

read more

Hypertensive crisis in children with chronic kidney disease after instituting antitubercular therapy: A case series

Tuberculosis is common in chronic kidney disease (CKD).There are reports of adults with CKD experiencing hypertensive crises and an increase in dosages and number of antihypertensive drugs after starting antitubercular therapy (ATT).Studies have demonstrated southwestern aztec rug that rifampicin could increase the metabolism of beta-blockers, calc

read more

What Promotes healing among the wrongfully convicted? Results from a qualitative study of exonerated persons in California

Background: Exonerees are individuals who have been wrongfully convicted of a crime.Later found innocent and released from prison, exonerees often spend decades incarcerated.While limited, research suggests that the unique trauma of wrongful conviction has profound adverse mental health implications which challenge reintegration, well-being and hea

read more